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Pharmaceutical

BioSafety offers many Chlorine Dioxide (CD) advantages to Pharmaceutical and Medical Device companies. Chlorine dioxide gas is emerging as an industry leader in contamination control technology, proving to be both practical and cost-effective. Our gaseous CD is the safest and most effective way to decontaminate isolators, processing rooms, and passthroughs. Our CD sterilizers effectively replace Ethylene Oxide (EtO) in many instances with an ambient temperature, highly effective sterilant gas that has exceptional process monitoring and control for easy validation.

Biosafety using ClorDiSys Solutions technology can provide equipment for routine decontaminations of rooms, processing vessels, isolators, pass-through chambers, biological safety cabinets, and other applications.  Routine decontaminations can be performed as part of a preventative maintenance, or routine contamination control schedule. 

Service decontaminations are also available to facilities that require either one-time or routine decontaminations as well.  We have experience in beta-lactam inactivation, and can aid in the repurposing of beta-lactam facilities for other uses.  Applications range from single rooms of any size to entire facilities, including HVAC ductwork and equipment.

In the pharmaceutical and medical device industry, contamination control and sterility are crucial components to maintaining the highest level of quality products expected of companies in these fields. ClorDiSys Solutions offers many chlorine dioxide based decontamination products and services to preserve your product integrity and trust. Our gaseous CD is gentle on materials and is the safest and most effective way to decontaminate your isolators, processing rooms, and passthroughs and is a direct replacement for EtO and hydrogen peroxide based systems.

Our chlorine dioxide gas is registered with US Environmental Protection Agency as a sterilant and is able to inactivate all forms of antimicrobial life, including spores. Our process has also been validated and proven to be effective at inactivating Beta-lactams including Penicillins, Cephalosporins, and Carbapenums allowing facilities of this type of contamination to be easily re-purposed. Download CloDiSys' paper from Applied Biosafety, Vol.16, No. 1, Chlorine Dioxide Gas Inactivation of Beta-Lactams for complete information.

ClorDiSys offers both equipment and services for decontamination as part of emergency response plans, preventative maintenance programs or contamination control schedules, when outbreaks occur, or for new construction, renovation or decommissioning projects.

Beta-Lactam Inactivation

Available Products: Clordisys Decontamination Services | Megadox | Cloridox-GMP | Minidox-M
Chlorine dioxide gas is proven effective against Beta-Lactams, and can inactive them on equipment or in rooms so that there is no risk of allergic exposure. After inactivation, equipment can be used on non-Beta-Lactam pharmaceuticals with no risk of contamination.
Penicillin Decon Read ClorDiSys article on Beta-Lactam inactivation in Applied Biosafety
Kevin Lorcheim
Applied Biosafety, Vol 16 No. 1 | ABSA, 2011

Rooms/Partial Facilities

Available Products: Clordisys Decontamination Services | Megadox | Cloridox-GMP | Minidox-M | Minidox-B
Single rooms, connected rooms, and other areas within facilities can be decontaminated using chlorine dioxide gas on a routine basis. Chlorine dioxide gas can also be used in contamination response to eliminate any contamination present and quickly return rooms and the equipment within back to a clean state. Typically all equipment and components within a facility is compatible with chlorine dioxide gas. By using a gas, all surfaces including cracks and crevices are contacted, allowing for complete decontamination of areas over 1,000,000 ft3
Laboratory Pharmaceutical Lab

Complete Facilities

Available Products: Clordisys Decontamination Services
Chlorine dioxide gas fills the space its contained in completely and evenly, making full facility decontamination easy as no surface is left untouched. We have decontaminated facility's over 1,000,000 ft3, providing sporicidal kill throughout. Suitable for new facilities prior to production starting, existing facilities during scheduled shutdown, after renovation, or if contamination is present.
Pharaceutical Facility Pharaceutical Facility

Isolators

Available Products: Cloridox-GMP | Minidox-M | Minidox-B
Chlorine dioxide gas decontamination of isolators is quick, residue free, and cycle development free. Isolators can be decontaminated in under an hour whether they are empty or full of components.
Isolator Isolator

Laboratories

Available Products: Clordisys Decontamination Services | Megadox | Cloridox-GMP | Minidox-M | Minidox-B
Laboratories can easily be decontaminated with chlorine dioxide gas. Equipment and components can all be left in place during the decontamination as chlorine dioxide gas is able to distribute around objects, completely and evenly contacting all surfaces within the room. Chlorine dioxide gas is safe on materials, even electronics.
Microscope Laboratory

HVAC Ductwork/HEPA Housings

Available Products: Clordisys Decontamination Services | Cloridox-GMP | Minidox-M
Ductwork and HVAC systems, including HEPA housings, can be decontaminated using chlorine dioxide gas. In fact, chlorine dioxide gas is the only residue free fumigation method that can successfully decontaminate HVAC ductwork as it does not condense out along the path length.
Autoclave Decontamination Room

Sterilizers

Available Products: Cloridox-GMP
Existing Autoclaves can be converted to replace steam or add the functionality of chlorine dioxide gas. Using chlorine dioxide gas instead of steam allows customers considerable utilities and consumable savings.
Decontamination Chamber Isolator

Decontamination Chambers

Available Products: Cloridox-GMP | Minidox-M | Minidox-B
Chlorine dioxide gas decontamination chambers offer many benefits to facilities who have them. Decon Chambers offer an easily sealed room where items can be brought in and quickly decontaminated. They can be used to bring equipment into a clean facility or out of a contaminated facility. Decon Chamber / Rack Washer combos add flexibility to a facility's capabilities, as one chamber can be used for either application. Using chlorine dioxide gas allows for the decontamination of heat / steam sensitive components such as electronics, tools, supplies and HEPA filters. click here to read more
Decontamination Chamber Isolator

Processing Equipment

Available Products: Clordisys Decontamination Services | Cloridox-GMP | Minidox-M | Minidox-B
Single pieces of equipment or rooms of equipment can be decontaminated with chlorine dioxide gas. Equipment can be tented / bagged and decontaminated, with cracks, crevices, nooks and crannies all being fully decontaminated.
Processing Equipment Processing Equipment

Lyophilizers

Available Products: Cloridox-GMP
Lyophilizers can be decontaminated with chlorine dioxide gas prior to use or on a routine basis to ensure sterility. Chlorine dioxide gas can also be used in contamination response to eliminate any contamination present. Chlorine dioxide gas will not stress the chamber and gaskets like steam can. Chlorine dioxide gas also offers a shorter cycle time as heat up and cool down is not required.
Lyophilizer Lyophilizer

Piping

Available Products: Cloridox-GMP | Minidox-M
Piping and filling lines can be decontaminated with chlorine dioxide gas upon installation to establish sterility. They can also be decontaminated on a routine basis, in response to a contamination, or after any maintenance is performed on the line. Using chlorine dioxide gas, all surfaces are guaranteed to be contacted.
Transfer Piping Transfer Piping

Biological Safety Cabinets

Available Products: Cloridox-GMP | Minidox-M | Minidox-B
Biological Safety Cabinets are able to be decontaminated with chlorine dioxide gas quickly and effectively. Chlorine dioxide gas and formaldehyde are currently the only decontaminating agents approved by NSF for BSC decontamination. Chlorine dioxide gas is able to reach all surfaces within the cabinet, including the area under the workstation, and the actual HEPA Filter itself.
Biological Safety Cabinet Biological Safety Cabinet

 

Please call Biosafety on 1300 379 996 or info@biosafety.com.au to discuss your needs.